UX Hero points out a technique that you may not be using, but should consider. Stepping back and squinting to evaluate your work is something I was told to do repeatedly when I was first learning to paint, and is something I still do today as an interface designer. It helps you see the whole of your screen and look for anything that stands out, and see what needs to draw more attention, depending on the priority and hierarchy of your page elements.
It's certainly useful for visual designers, but can be just as useful for interface designers. Another thing I do related to this is zoom out and turn my wireframes into visual thumbnails on the screen.