Theresa Neil is writing a 6 part series of articles on designing great Adobe Flex/Air user experiences. The first 3 parts are up now.

After designing several large enterprise applications for diverse clients and industries, I’ve noticed some barriers to crafting a great experience in Flex. I think these barriers arise from the relative newness of the technology (and RIAs in general), the initial focus on development over design, and the confidence that Flex can provide a great UX out of the box. But it takes a bit more to make a Flex app really shine. Fortunately, the Flex community is chock-full of talented and motivated developers who contribute amazing resources.

http://designingwebinterfaces.com/great-flex-ux